| # | Metro | Startups | Population | Per 100,000 Residents |
|---|---|---|---|---|
| 1 | Pittsburgh | 260 | 2,443,921 | 10.64 |
| 2 | Portland — the Silicon Forest | 236 | 2,510,529 | 9.40 |
| 3 | Boulder | 11 | 328,317 | 3.35 |
| 4 | Walla Walla | 2 | 62,102 | 3.22 |
| 5 | Youngstown | 13 | 428,430 | 3.03 |
| 6 | the Research Triangle | 64 | 2,287,314 | 2.80 |
| 7 | Spokane | 13 | 591,793 | 2.20 |
| 8 | Greater Atlanta | 132 | 6,176,937 | 2.14 |
| 9 | New Orleans | 19 | 988,763 | 1.92 |
| 10 | the DMV (DC, Maryland, Virginia) | 87 | 6,263,796 | 1.39 |
| 11 | Baton Rouge | 10 | 871,379 | 1.15 |
| 12 | Bozeman & Greater Yellowstone | 6 | 529,288 | 1.13 |
| 13 | Greater Cleveland | 20 | 2,171,978 | 0.92 |
| 14 | Las Vegas | 19 | 2,293,764 | 0.83 |
| 15 | Idaho (Boise) | 15 | 1,893,296 | 0.79 |
| 16 | Greater Columbus | 17 | 2,151,847 | 0.79 |
| 17 | the Twin Cities | 27 | 3,693,351 | 0.73 |
| 18 | Greater St. Louis | 19 | 2,809,414 | 0.68 |
| 19 | Richland | 2 | 307,900 | 0.65 |
| 20 | Detroit | 23 | 4,367,620 | 0.53 |
| 21 | Northwest Arkansas | 3 | 563,436 | 0.53 |
| 22 | Silicon Valley | 46 | 9,101,124 | 0.51 |
| 23 | Denver | 14 | 2,977,085 | 0.47 |
| 24 | Seattle | 19 | 4,021,467 | 0.47 |
| 25 | Upstate New York | 26 | 7,008,487 | 0.37 |
| 26 | Austin | 7 | 2,357,497 | 0.30 |
| 27 | Houston | 17 | 7,274,714 | 0.23 |
| 28 | Monterey | 1 | 435,834 | 0.23 |
| 29 | Dallas | 11 | 5,252,554 | 0.21 |
| 30 | Philadelphia | 13 | 6,241,882 | 0.21 |
| 31 | New England | 10 | 4,917,661 | 0.20 |
| 32 | Greater San Diego | 5 | 3,282,782 | 0.15 |
| 33 | New York City | 26 | 19,756,722 | 0.13 |
| 34 | Greater Chicago | 10 | 9,359,555 | 0.11 |
| 35 | Fort Worth | 2 | 2,555,001 | 0.08 |
| 36 | Greater Orlando | 2 | 2,721,022 | 0.07 |
| 37 | Tampa Bay | 2 | 3,240,469 | 0.06 |
| 38 | Greater Los Angeles | 7 | 13,012,469 | 0.05 |
| 39 | Greater Miami / South Florida | 3 | 6,138,876 | 0.05 |
| 40 | Nashville | 1 | 2,043,713 | 0.05 |
| 41 | Greater San Antonio | 0 | 2,612,802 | 0.00 |
| 42 | the Sun Belt — Arizona | 0 | 7,268,175 | 0.00 |